Figure 2
From: The Akt pathway in human breast cancer: a tissue-array-based analysis
Examples of PTEN protein expression levels observed in invasive breast cancers by immunohistochemistry. (a) Normal expression. Invasive cancer cells with staining intensity equal to normal. (b) Reduced expression. Cancer cells showing staining intensity less than that noted in the adjacent endothelial cells. (c) Loss of expression. No staining is seen in cancer cells while endothelial cells stain normally.
