Figure 4
From: Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma
EGFR gene mutations in a synovial sarcoma. The nucleotide sequences of the EGFR exons 19 and 21 showed tumor-specific mutations (double peaks). Both sense and antisense directions are displayed. The wild-type nucleotide sequences are shown above the diagrams with mutated nucleotides listed in the line below. The point mutations result in a proline to serine substitution in exon 19 (P733S) and in alanine to threonine substitution in exon 21 (A840T). The first c to t replacement in exon 19 does not lead to an amino-acid substitution.
