Table 4 Statistical analysis of immunohistochemical results

From: Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers

Antibodies

Statistical significance

 

χ 2

Binary logistic regression model

 

Age

Age

Location

Histology

E-Cadherin

P=0.027

None

None

P<0.001 (CI 3.2–16.3)

β-Catenin

P=0.049

None

None

None

p53

P=0.009

None

P=0.004 (CI 0.2–0.7)

None

COX-2

P<0.001

P<0.001 (CI 6.3–50.1)

None

P=0.008 (CI 0.1–0.7)

TFF1

P<0.001

P=0.001 (CI 1.7–7.6)

None

P=0.04 (CI 0.2–0.97)

HuR cytoplasmic

P=0.005

None

None

None

HuR nuclear

None

None

None

None

C/EBP-β

P=0.033

None

None

P=0.001 (CI 0.08–0.52)

p16

P=0.001

None

P=0.014 (CI 1.2–5.6)

None

c-myc

P=0.015

None

None

None

c-jun

P=0.08

None

P=0.012 (CI 1.3–6.1)

None

  1. χ2 test was carried out for each antibody vs age. The results displayed under the heading Binary logistic regression model are as follows: age, adjusted for location and histology; location, adjusted for age and histology; and histology (results for diffuse histology given) adjusted for age and location.
Back to article page