Table 3 Sensitivity, specificity, positive and negative predictive value of low podoplanin expression to predict tumor progression/recurrence and poor overall outcome (dying from disease) in cervical squamous cell carcinomas

From: Low podoplanin expression in pretreatment biopsy material predicts poor prognosis in advanced-stage squamous cell carcinoma of the uterine cervix treated by primary radiation

 

Sensitivity

Specificity

PPV

NPV

RR (95% CI)

All cases (series A and B) combined

 Recurrence

0.5294

0.7692

0.7500

0.5556

1.69 (1.24–2.30)

 Dying from disease

0.3676

0.9231

0.8621

0.5275

1.82 (1.41–2.37)

Advanced stage cases treated by primary radiation

 Recurrence

0.6579

0.6765

0.6944

0.6389

1.92 (1.18–3.13)

 Dying from disease

0.5526

0.8824

0.8400

0.6383

2.32 (1.53–3.52)

  1. PPV, positive predictive value; NPV, negative predictive value; RR, relative risk; CI, confidence interval.
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