Table 1 Diagnostic criteria for Waldenström macroglobulinemia recommended by the Second International Workshop on Waldenström macroglobulinemia

From: Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia and does not correlate with p65 NF-κB activation

Criteria

• IgM monoclonal gammopathy of any concentration

• Bone marrow infiltration by small lymphocytes showing plasmacytoid/plasma cell differentiation

• Intertrabecular pattern of bone marrow infiltration

• Surface IgM+, CD5±, CD10−, CD19+, CD20+, CD22+, CD23−, CD25+, CD27+, FMC7+, CD103−, CD138− immunophenotype.

Back to article page