Figure 1 | Modern Pathology

Figure 1

From: Diversity of epidermal growth factor receptor-mediated activation of downstream molecules in human lung carcinomas

Figure 1

The results of immunohistochemical staining for EGFR and p-Stat-3 as well as FISH analysis. A case of squamous cell carcinoma (a, Hematoxylin–Eosin staining) which was confirmed to have EGFR amplification (Case 3), showing intense positive membrane staining of EGFR (b), and positive nuclear staining for p-Stat-3 (c) in the peripheral area of the tumor nest. (d) Tumor cells with four copies of scattered signals of EGFR (orange) were observed by FISH analysis. Original magnification, × 400.

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