Table 2 Overall data of the tissues examined
Case | Histology | Immunohistochemistry | Immunobltting analysis | FISH a | Mutation | Metastasis | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EGFR | p-EGFR | p-Stat3 | p-Akt | p-Erk | EGFR | p-EGFR | p-Stat3 | p-Akt | p-Erk | ||||||
1 | ACb | Mixc | 2+ | 1+ | 1+ | − | − | 7.33 d | 4.00 | 3.15 | 1.25 | 0.44 | + | + | |
2 | SCCe | 2+ | − | 1+ | − | − | 4.86 | 1.33 | 4.67 | 1.38 | 2.24 | + | + | ||
3 | SCC | 2+ | − | 1+ | − | − | 6.25 | 1.85 | 3.15 | 1.00 | 0.55 | + | |||
4 | SCC | 2+ | − | 1+ | − | − | 7.00 | 1.90 | 2.93 | 1.14 | 1.00 | + | |||
5 | AC | Mix | 2+ | 1+ | 1+ | − | − | 5.60 | 3.50 | 3.64 | 1.00 | 0.59 | + | S695R | |
6 | AC | Mix | − | − | − | 1+ | − | 1.63 | 5.00 | 1.25 | 2.32 | 2.09 | del747-753insS | + | |
7 | AC | Mix | 1+ | 1+ | − | 1+ | − | 2.40 | 4.10 | 1.38 | 4.90 | 1.00 | del747-752 | + | |
8 | AC | Mix | − | − | − | 1+ | − | 2.20 | 2.75 | 1.09 | 4.13 | 1.06 | L858R | + | |
9 | AC | Mix | 1+ | 1+ | − | 1+ | − | 3.29 | 5.00 | 1.13 | 3.33 | 0.65 | L858R | ||
10 | SCC | 2+ | − | 1+ | − | − | 2.80 | 1.90 | 3.80 | 1.18 | 1.20 | ||||
11 | SCC | 2+ | − | − | − | 1+ | 4.29 | 1.57 | 1.08 | 1.04 | 2.23 | ||||
12 | AC | Mix | 1+ | − | 1+ | − | − | 2.25 | 1.30 | 2.60 | 1.25 | 2.20 | |||
13 | AC | Mix | 1+ | − | 1+ | − | − | 1.90 | 1.90 | 2.40 | 0 | 1.60 | |||
14 | AC | Mix | 1+ | − | − | − | − | 1.60 | 1.25 | 2.86 | 1.31 | 0.50 | |||
15 | SCC | 1+ | − | − | 1+ | − | 2.60 | 0 | 1.17 | 1.67 | 0.93 | + | |||
16 | AC | Mix | − | − | 1+ | 1+ | − | 0 | 1.25 | 3.33 | 1.70 | 0.50 | |||
17 | AC | Mix | − | − | − | − | − | 0 | 0 | 1.29 | 1.60 | 1.50 | |||
18 | AC | Mix | − | − | − | − | − | 1.70 | 2.00 | 2.00 | 1.29 | 1.10 | |||
19 | AC | Mix | − | − | − | 1+ | − | 1.40 | 0 | 1.40 | 3.60 | 0.50 | + | ||
20 | AC | Mix | − | − | − | − | 1+ | 1.33 | 1.22 | 1.11 | 1.60 | 2.70 | |||
21 | AC | Mix | − | − | 1+ | − | − | 1.20 | 0 | 4.25 | 1.22 | 0.50 | |||
22 | AC | Papf | − | − | 1+ | − | 1+ | 1.25 | 0 | 2.30 | 1.20 | 2.00 | |||
23 | AC | Solidg | − | − | − | − | − | 1.43 | 1.10 | 1.25 | 1.00 | 2.50 | |||
24 | SCC | − | − | − | 1+ | 1+ | 1.25 | 1.00 | 1.10 | 1.60 | 4.30 | ||||
25 | SCC | − | − | − | 1+ | − | 1.29 | 1.43 | 1.00 | 2.00 | 1.50 | ||||
26 | SCC | − | − | − | 1+ | − | 1.63 | 0 | 1.22 | 2.00 | 1.50 | ||||
27 | SCC | − | − | − | 1+ | 1+ | 1.11 | 0 | 1.30 | 2.90 | 3.10 | + | |||
28 | LCh | − | − | 1+ | 1+ | − | 1.00 | 0 | 1.82 | 2.13 | 1.25 | ||||
Cont1 | bulla | − | − | − | − | − | 0.30 | 0 | 0.29 | 0.11 | 0.90 | ||||
Cont2 | bulla | − | − | − | − | − | 0.20 | 0 | 0.19 | 0.15 | 1.20 |