Table 1 FHIT expression by IHC, methylation status of FHIT protein and characteristics of patient with diffuse large B-cell lymphoma
| Â | FHIT methylation analysis | FHIT protein expression level (IHC) | ||||
|---|---|---|---|---|---|---|
| Â | na | Methylated (%) | P-value | na | Reduced/lost (%) b | P-value |
Age (years) | ||||||
 ≤25 | 10 | 30 | 0.3015 | 18 | 83 | 0.0025 |
 25–50 | 41 | 15 |  | 47 | 62 |  |
 50–75 | 38 | 26 |  | 44 | 71 |  |
 >75 | 4 | 50 |  | 5 | 0 |  |
Stage | ||||||
 1 | 12 | 17 | 0.1577 | 12 | 67 | 0.5985 |
 2 | 28 | 11 |  | 28 | 72 |  |
 3 | 2 | 0 |  | 2 | 67 |  |
 4 | 3 | 67 |  | 3 | 40 |  |
Subtype | ||||||
 Germinal center | 8 | 13 | 0.3619 | 10 | 90 | 0.0558 |
 Nongerminal center | 45 | 27 |  | 57 | 61 |  |
