Figure 5

Immunohistochemistry for EphA1 of skin ulcers. (a) Keratinocytes adjacent to the rim of the ulcer show an intense cytoplasmic staining pattern. (b) Keratinocytes distant from the rim of the same ulcer show the typical network staining pattern of EphA1, caused by an accentuated expression of this receptor at the membrane of the keratinocytes.