Figure 1

Necroinflammatory activity in chronic hepatitis. A 62-year-old woman with hepatitis C undergoes needle biopsy for grading and staging of her disease. A portal tract is expanded by a predominantly mononuclear cell infiltrate. Although the limiting plate is intact along most of its extent, there is interface hepatitis breaching it on the right-hand side, including inflammation and an acidophil body. Likewise, in foci of lobular hepatitis toward the left, inflammation is seen with and without acidophil bodies. (H&E, × 10 original magnification).