Figure 8
From: Liver biopsy assessment in chronic viral hepatitis: a personal, practical approach
Large cell change. Large hepatocytes are easily seen scattered among the normal size, regenerating hepatocytes. They are large cells with large, often hyperchromatic and atypical appearing nuclei. Multinucleation may be common. Despite their ‘dysplastic’ appearance, they have a relatively normal nuclear: cytoplasmic ratio (H&E, original magnification × 20).
