Figure 3
From: Chronic myelomonocytic leukemia: the role of bone marrow biopsy immunohistology

(a) Bone marrow biopsy of a case of CMML. Plasmacytoid monocyte nodules, as the one shown here, are often inapparent in H&E-stained bone marrow sections. If detected, in the absence of immunohistochemistry, are difficult to distinguish from aggregates of immature myeloid cells. (b) Immunohistochemical staining for CD123 highlights a large nodule of plasmacytoid monocytes and greatly helps in the identification of these cells.