Table 5 The most frequent CGH alterations in transformed diffuse large B-cell lymphoma in relation to the total number of alterations

From: Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma

Tumo no.

No. of alterations

4q13–21

+Xq25–26

8p22-pter

9p23-pter

+7pter-q22

+1q31–32

+12q15

+18q21

6q16–21

+11q22

17p

+13q22

22q

+3q24–25

3

0

              

23:2

1

−4q

             

24:2

2

 

+Xq21-qter

            

4

2

  

−8p22-pter

−9p23-pter

          

21:2

2

    

+7

+1q

        

27:2

2

              

7

3

    

+7

         

6

3

      

+12pter-q22

       

5

3

 

+Xp11-q26

−8p22-pter

−9p22-pter

          

20:2

3

              

22:2

4

  

−8p

   

+12q13–15

+18q21

      

8

4

−4q10–22

     

+12pter-q22

+18q

−6q14–21

     

17:2

4

 

+X

    

+12q10–21

       

30:5

4

 

+X

   

+1q

  

−6q

     

19:2

4

       

+18pter-q21

−6q15–23

+11

−17p

   

25:2

4

 

+X

     

+18q

 

+11

    

28:2

4

 

+Xq25-qter

  

+7

         

28:3

4

 

+X

  

+7

         

12:2

4

     

+1q

        

15:2

5

       

+18q12–22

 

+11q14–22

 

+13q12–22

  

12:1

5

     

+1q

        

30:6

5

 

+X

   

+1q

+12

 

−6q

     

27:3

5

 

+X

     

+18pter-q21

      

9

6

        

−6q16-qter

+11q13–22

    

26:2

7

   

−9p

      

−17p

   

10

7

−4q13–21

 

−8p12-pter

  

+1q31-qter

+12p11–q21

  

+11q22–23

    

14:1

8

 

+X

  

+7

   

−6q

 

−17p

   

16:2

8

−4q21-qter

+Xq

−8p

       

−17p

   

18:1

9

      

+12q15–22

       

11

9

    

+7pter-q22

         

13:2

10

 

+X

  

+7

 

+12p12-q21

 

−6p21-q21

   

−22q

 

13:1

11

−4pter-q21

   

+7

 

+12p12-q21

 

−6p21-q21

     

29:4

12

    

+7pter-q31

   

−6q14–25

 

−17p

+13q22-qter

 

+3q25-qter

14:2

12

 

+X

  

+7

   

−6q

 

−17

   

14:3

12

 

+X

  

+7

   

−6q

 

−17

   
  1. Bold style indicates a high-level amplification.