Table 6 Acquired alterations in transformed DLBCL from the 16 studied cases with matched follicular lymphoma and DLBCL tumors

From: Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma

Case

Acquired CGH alterations in DLBCL (total number and regions involved)

 

>2a (frequent)

2 a (less frequent)

<2a (rare)

15

 

+4q31-qter

13q12–22

  

+11q14–22

18q12–22

   

−9q22

16

+Xq,

−1p32-pter

+9q22-qter

 

+8q21-qter

−8p

−15

 

−4q21-qter

−17p

 

17

 

+12q10–21

−16q21–23

18

+8q12–24

+4q

+2q22–33

  

+12q15–22

+6q10–21

   

+9p

   

+12p12

   

−6p21

   

−11q12–13

19

−6q15–23

+11

 

20

   

21

+7

  

22

 

−8p

 
  

−19pter-13.2

 

23

−4q

  

24

+Xq21-qter

+11p

 

25

+X

  

26

 

−1p21–32

 
  

−19p

 

27

+8q21.3-qter

 

+8p

28

+7

 

+2p14–16

29

+7pter-q31

−17p

+3q25-qter

 

+8q10–22

 

+10p

 

−4q32–33

 

−13q22-qter

 

−6q14–25

 

−X

30

−6q

 

+17q

  1. DLBCL, diffuse large B-cell lymphoma.
  2. a>2, 2, and <2 indicate the no. of cases in which each specified alteration was observed. Each alteration in subsequent DLBCL relapses from the same case was counted once.