Figure 3
Panlobular hemosiderin accumulation in Type 1 HH. In this case, the entire lobule has accumulated iron (‘grade 4’) and the measured iron content was 23 000 μg/g dry weight liver. This represents highly penetrant HH regardless of age, this liver is at high risk of developing significant fibrosis in the near-term, and the likelihood of extrahepatic manifestations of HH high as well.
