Table 4 High expression of HIF-1α in type I endometrial adenocarcinoma and its correlation with tumor characteristics
From: Increased expression of hypoxia-inducible factor 1α in type I and type II endometrial carcinomas
Type I endometrial adenocarcinoma (n=108) | High expression of HIF-1α (n=20) | P-value |
|---|---|---|
Grade (n=94, missing 14) | ||
Low (n=42) | 4 (9.5%) | 0.009 |
Higha (n=66) | 16 (24%) | |
Myometrial invasion (n=101, missing 7) | ||
None (n=31) | 5 (16%) | 0.05 |
Inner (n=41) | 5 (12%) | |
Outer (n=29) | 10 (34%) | |
Adnexal invasion (n=105, missing 3) | ||
No (n=96) | 12 (12.5%) | 0.02 |
Yes (n=9) | 8 (89%) | |
Vascular invasion (n=105, missing 3) | ||
No (n=64) | 9 (14%) | 0.06 |
Yes (n=41) | 11 (27%) | |
Stage (n=105, missing 3) | ||
Low (n=92) | 10 (11%) | <0.01 |
High (n=13) | 10 (77%) | |
