Table 2 Immunohistochemistry of the EGFR, androgen receptor, Her2/neu, and c-kit in stromal and epithelial components of phyllodes tumors of the prostate

Case	EGFR ^a				HER-2 ^b				c-kit				Androgen receptor
	Stroma		Epithelium		Stroma		Epithelium		Stroma		Epithelium		Stroma		Epithelium
	Intensity	%	Intensity	%	Intensity	%	Intensity	%	Intensity	%	Intensity	%	Intensity	%	Intensity	%
1	1	20	3	100	0	0	1	60	0	0^c	0	0	1	1	2	30
2	0	0	3	98	0	0	0	0	0	0^c	1	2	2	30	2	40
3	1	1	3	100	0	0	1	2	0	0^c	0	0	1	10	2	30
4	3	60	3	100	0	0	0	0	0	0^c	0	0	0	0	0	0
5	0	0	3	100	0	0	1	10	0	0	0	0	3	50	3	95
6	0	0	3	100	0	0	0	0	0	0^c	0	0	0	0	0	0
7	3	70	3	98	0	0	0	0	0	0	0	0	0	0	0	0
8	0	0	3	100	0	0	1	20	0	0^c	0	0	3	20	3	60
9	0	0	3	98	0	0	0	0	0	0^c	1	5	2	15	3	80
10	0	0	3	95	0	0	0	0	0	0	0	0	NA	NA	NA	NA
11	3	40	3	40	0	0	0	0	0	0	0	0	3	80	3	90

All stains intensity graded as: 0, 1+, 2+, 3+.
NA, not applicable.
^aBasal cells staining strongly positive, luminal epithelial cells staining negative or weakly positive.
^bEpithelium showing weak positivity in four cases.
^cFocal staining in stromal mast cells, not in tumor cells.

Quick links

Search