Table 3 Immunophenotypic profile of four cases of ALK-DLBCL
From: ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literature
Antibody | Case 1 | Case 2 | Case 3 | Case 4 |
|---|---|---|---|---|
CD20 | Rare + | Neg | Neg | Neg |
CD79a | Variably + | Neg | Scattered + | Neg |
CD138 | + | + | + | + |
VS38 | + | + | + | ND |
EMA | Variably + | + | Scattered + | + |
Kappa, poly | + | Neg | Neg | Neg (ISH) |
Lambda, poly | Neg | + | + | + (ISH) |
CD30 | Neg | Neg | Neg | Neg |
ALK-1 | + | + | + | + |
CD4 | Patchy + | + (FC) | Patchy + | Weak + |
CD3 | Neg | Neg | Neg | Neg |
CD45 | Variably + | + (FC) | + | + |
CD57 | Neg | Patchy + | Patchy + | ND |
CD38 | Neg | + (FC) | Neg | Neg |
IgA | Equivocal | Equivocal | Equivocal | ND |
CD43 | Rare + | Rare + | Neg | Rare + |
CD56 | Neg | Neg | Neg | ND |
TIA-1 | Neg | Neg | Neg | Neg |
Ki-67 | 50% | 50% | 80% | 50% |
Cytokeratin (AE1/AE3) | Neg | Scattered + | Neg | Neg |
