Figure 1
From: Prognostic significance of angiogenesis in gastrointestinal stromal tumor
Histological and immunohistochemical findings in GIST (a, b). (a) GIST, spindle-cell type. Spindle cells proliferate in fascicles. (b) Immunohistochemical stain for c-kit. Tumor cells are diffusely positive. Immunohistochemical staining with CD31 for quantification of MVD in GIST (c, d). (c) GIST showing low MVD (2.8/0.95 mm2). (d) GIST showing high MVD (40.4/0.95 mm2). Immunohistochemical staining for VEGF expression in GIST (e, f). (e) Very weak expression of VEGF in tumor cells. (f) Strong expression of VEGF in tumor cells.
