Figure 2

Kaplan–Meier analysis for 80 patients with GIST. (a) Twenty-four patients with high-grade GIST have significantly shorter DFS than 26 patients with very low+low-grade GIST and 30 patients with intermediate-grade GIST (P<0.0001). (b) Thirty-five patients with large tumor size (≥5 cm) have significantly shorter DFS than 45 patients with small size (<5 cm) (P=0.0199). (c) Thirty-six patients with high-mitotic counts (≥5/50 HPF) have significantly shorter DFS than 44 patients with low counts (<5/50 HPF) (P=0.0055). (d) Forty-one patients with high Ki-67 LI (≥4.6%) have a significantly shorter DFS than 39 patients with a low index (<4.6%) (P=0.0027). (e) Forty-three patients with many MVD (≥7.0) also have a significantly shorter DFS than 37 patients with little MVD (<7.0) (P=0.0028). (f) Forty patients with high VEGF expression also have a significantly shorter DFS than 40 patients with a low VEGF expression (P=0.0302).