Table 2 Correlation between MVD and clinicopathological factors

From: Prognostic significance of angiogenesis in gastrointestinal stromal tumor

Factors

MVD (/0.95 mm2)a

P-value

Age (year)

 

0.7265

 <64 (n=47)

8.3 (2.4–11.1)

 

 ≥64 (n=48)

5.8 (2.4–13.1)

 

Gender

 

0.0399

 Male (n=48)

9.4 (4.3–13.5)

 

 Female (n=47)

4.6 (2.0–10.4)

 

Site

 

0.0422

 Stomach (n=64)

6.7 (1.8–10.8)

 

 Intestine (n=31)

9.0 (4.6–19.9)

 

Size

 

0.0006

 <5 cm (n=39)

4.1 (1.6–9.0)

 

 ≥5 cm (n=56)

9.4 (4.1–15.3)

 

Cell type

 

0.5656

 Spindle (n=92)

6.9 (2.4–11.6)

 

 Epithelioid and mixed (n=3)

11.2 (4.1–23.5)

 

Mitosis

 

0.6785

 <5/50 HPF (n=55)

6.3 (2.4–11.7)

 

 ≥5/50 HPF (n=40)

8.2 (2.4–11.3)

 

Tumor grade

 

0.0359

 Very low+low (n=29)

4.6 (1.7–9.4)

 

 Intermediate (n=38)

8.3 (2.4–11.8)

 

 High (n=28)

8.7 (3.4–14.6)

 

Ki-67 index

 

0.2579

 <4.6% (n=47)

5.1 (1.7–11.4)

 

 ≥4.6% (n=48)

8.5 (3.6–11.8)

 

VEGF expression

 

<0.0001

 Low (n=50)

3.6 (1.6–9.1)

 

 High (n=45)

10.4 (4.9–17.3)

 
  1. MVD, microvessel density; HPF, high-power field; VEGF, vascular endothelial growth factor.
  2. aValues were expressed as median levels (interquartile range).