Figure 1 | Modern Pathology

Figure 1

From: Prognostic significance of maspin in pancreatic ductal adenocarcinoma: tissue microarray analysis of 223 surgically resected cases

Figure 1

Immunohistochemical staining of maspin in pancreatic ductal adenocarcinomas and PanINs. About 94% pancreatic ductal adenocarcinomas are immunohistochemically positive for maspin, the vast majority of them are diffusely positive (a) and a small percentage of them are focally positive (b). Normal ductal epithelium is negative for maspin (c). A small percentage of carcinomas also had nuclear staining of maspin in addition to cytoplasmic labeling (d). About 50% low-grade PanINs (PanIN1a— e and PanIN1b— f) and about 80% high-grade PanINs (PanIN2— g and PanIN3— h) are also immunohistochemically positive for maspin.

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