Table 1 Comparison of clinicopathologic factors between patients whose tumors showed no expression and patients whose tumors showed expression of maspin
Clinicopathologic factors | Maspin status | P-value | |
|---|---|---|---|
No expression (n= 14) | With expression (n=209) | ||
Postoperative survival at 40 months (%) | 6 of 14 (42%) | 45 of 209 (21%) | 0.095 |
Median postoperative survival (months) | 29.5 | 17 | 0.053 |
Mean age, years, at the time of surgery (range) | 68.9±11.1 (51–84) | 65.5±11.2 (32–89) | 0.2908 |
Gender (male:female) | 10:4 | 107:102 | 0.4143 |
Mean tumor size, cm (range) | 2.8±1.1 (1.5–5.0) | 3.2±1.6 (1–15.5) | 0.2655 |
Tumor differentiation | |||
Well to moderate | 10 | 112 | 0.5820 |
Poor | 4 | 97 | |
Tumor pathologic stage | |||
pT1 | 0 | 1 | 0.5182 |
pT2 | 1 | 5 | |
pT3 | 13 | 199 | |
pT4 | 0 | 4 | |
Lymph node status | |||
N0 | 2 | 36 | 1.00 |
N1a | 1 | 34 | |
N1b | 11 | 139 | |
Mean number of positive nodes in all patients, N0 and N1 (range) | 4.7±4.1 (0–15) | 4.1±4.4 (0–25) | 0.5989 |
Mean number of positive nodes in N1 patients (range) | 5.5±3.9 (1–15) | 4.9±4.3 (1–25) | 0.6400 |
Vascular invasion | 8 (57%) | 99 (48%) | 0.2772 |
Perineural invasion | 14 (100%) | 195 (94%) | 1.00 |