Figure 5

Expression of MUC1 and surfactant apoprotein A in carcinoma cells with micropapillary patterns (a, c, e, g: MUC1 immunohistochemistry; b, d, f, h: surfactant apoprotein A immunohistochemistry). c, d, g, h are high-magnification images of a, b, e, f, respectively. MUC1 showed high expression over the whole surface of the micropapillary pattern (a, c, e, g), while surfactant apoprotein A expression tended to be low in micropapillary pattern areas (b, d), with some exceptions (f, h). Surfactant apoprotein A was expressed mainly in the cytoplasm of cancer cells in the micropapillary pattern area (f, h).