Table 3 Correlation between micropapillary pattern status and gene expression levels in small-size lung adenocarcinoma
Gene expression | No. of patients | Micropapillary pattern status | P-value | ||
|---|---|---|---|---|---|
Negative (n=164) | Positive (n=21) | ||||
MUC1 | Low (0–3+) | 48 | 14 (7.6) | 0 (0) | 0.16 |
High (4+) | 137 | 150 (81.1) | 21 (11.4) | ||
Surfactant apoprotein | |||||
A | Low (0–2+) | 132 | 117 (63.2) | 15 (8.1) | 0.99 |
High (3+, 4+) | 53 | 47 (25.4) | 6 (3.2) | ||
MUC4 | Low (0, 1+) | 160 | 142 (76.8) | 18 (9.7) | 0.91 |
High (2+–4+) | 25 | 22 (11.9) | 3 (1.6) | ||
ERBb2 | Low (0, 1+) | 132 | 117 (67.6) | 15 (8.7) | 0.88 |
High (2+–4+) | 41 | 36 (20.8) | 5 (2.9) | ||
p27 | Low (0, 1+) | 115 | 98 (56.7) | 17 (9.8) | 0.06 |
High (2+–4+) | 58 | 55 (31.8) | 3 (1.7) | ||
CEA | Low (0) | 153 | 136 (73.9) | 17 (9.2) | 0.77 |
High (1+–4+) | 31 | 27 (14.7) | 4 (2.2) | ||
p16 | Low (0, 1+) | 85 | 72 (40.0) | 13 (7.2) | 0.09 |
High (2+–4+) | 95 | 88 (48.9) | 7 (3.9) | ||
MUC5AC | Low (0–2+) | 150 | 131 (70.8) | 19 (10.3) | 0.24 |
High (3+, 4+) | 35 | 33 (17.8) | 2 (1.1) | ||
