Table 1 National Cancer Institute TMA—comparison of tumors expressing high and low levels of JAG1 mRNA and protein

From: High-level JAG1 mRNA and protein predict poor outcome in breast cancer

 

n

10-year survival rate (95% CI)

Median survival (95% CI)

P

JAG1 mRNA

 Low

104

47% (36–57)

100 months (77–139)

<0.001

 High

23

16% (4–34)

43 months (12–71)

 

JAG1 protein

 Low

88

48% (36–59)

108 months (76–155)

0.03

 High

39

26% (13–41)

63 months (34–80)

 

JAG1 mRNA/protein

 Low/low

74

53% (40–64)

131 months (85–189)

0.055a

 Low/high

30

31% (15–49)

77 months (34–83)

<0.0001b

 High/low

14

19% (3–45)

43 months (19–102)

 

 High/high

9

11% (0–39)

23 months (11–71)

 
  1. aTest for interaction.
  2. bTest for any difference between the groups.