Table 2 Genes methylated in breast cancer
Gene | Description | Hypo/hyper | Reference |
|---|---|---|---|
1-SYNU-CLEIN | Human breast cancer-specific gene 1 | Hypo | |
c-myc | C-myelocytic leukemia | Hypo | |
MAGE | Melanoma-associated antigen | Hypo | |
NOEY2/ARHI | Ras homolog member 1 | Hypo | |
Sat2 | Satellite 2 | Hypo | |
SATR1/SATR2 | Satellite repeat 1/satellite repeat 2 | Hypo | |
UPA | Urokinase plasminogen activator | Hypo | |
14-3-3sigma | 14-3-3 sigma | Hyper | |
AK5 | Adenylate kinase 5 | Hyper | |
AMN | Amnionless homolog | Hyper | |
APC | Adenomatous polyposis coli | Hyper | |
BRCA1 | Breast cancer | Hyper | |
CDH1 | Cadherin 1 | Hyper | |
CDKN2A | Cyclin-dependent kinase inhibitor 2A | Hyper | |
DAPK1 | Death-associated protein kinase 1 | Hyper | |
DCC | Deleted in colorectal carcinoma | Hyper | |
DSC3 | Desmocollin 3 | Hyper | |
ER | Estrogen receptor | Hyper | |
FOXA2 | Forkhead box A2 | Hyper | |
GJB2 | Gap junction protein, beta 2 (Connexin 26) | Hyper | |
GSTP1 | Glutathione S-transferase pi | Hyper | |
HIC-1 | Hypermethylated in cancer 1 | Hyper | |
HIN-1 | Hairpin induced 1 | Hyper | |
HME-1 | Human epithelial cell marker 1 | Hyper | |
HOXD11 | Home box D11 | Hyper | |
KLK6 | Kallikrein 6 | Hyper | |
KLK10/NES1 | Kallikrein 10 | Hyper | |
LATS1/LATS2 | Large tumor suppressor 1 and 2 | Hyper | |
LKB1/STK11 | Serine/threonin protein kinase 11 | Hyper | |
MGMT | Methylguanine methyltransferase | Hyper | |
NORE1 | Novel Ras effector 1 | Hyper | |
p14ARF | p14 alternate reading frame | Hyper | |
P16INK4a | p16 INK 4a | Hyper | |
p57KIP2 | Cyclin-dependent kinase inhibitor 1C | Hyper | |
PCDH10 | Protocadherin 10 | Hyper | |
PR | Progesterone receptor | Hyper | |
Rad9 | Rad9 homolog | Hyper | |
RASSF1A | Ras-association domain family protein 1A | Hyper | |
RUNX3 | Human Runt-related transcription factor gene 3 | Hyper | |
SIM1 | Single-Minded homolog 1 | Hyper | |
TDH | L-threonine dehydrogenase | Hyper | |
TIMP-3 | Tissue inhibitor of metalloproteinases-3 | Hyper | |
TMS1 | Target of methylation-induced silencing 1 | Hyper | |
Tropomyosin | Tropomyosin | Hyper | |
TSPAN-2 | Tetraspan 2 | Hyper | |
Twist | Twist | Hyper | |
WT-1 | Wilms tumor 1 | Hyper | |
XT3 | X transporter protein 3 | Hyper |
