Table 1 Expression of biomarkers in ovarian tissue samples

From: Activation of BTAK expression in primary ovarian surface epithelial cells of prophylactic ovaries

Biomarker by tissue type

Expression level, n (%)

 

0

1

2

3

P-value

BTAK

 Normal ovaries (38)

29 (76)

7 (18)

2 (5)

0 (0)

<0.001a

 Ovaries with BRCA mutations or strong family history (21)

5 (24)

8 (38)

7 (33)

1 (5)

<0.001b

 Carcinoma (194)

0 (0)

2 (1)

146 (75)

46 (24)

<0.001c

p53

 Normal ovaries (38)

34 (89)

2 (5)

1 (3)

1 (3)

<0.001a

 Ovaries with BRCA mutations or strong family history (21)

14 (67)

0 (0)

4 (19)

3 (14)

0.023b

 Carcinoma (194)

55 (28)

23 (12)

20 (10)

96 (50)

<0.001c

  1. Reference: P-values reflect differences in proportions between anormal ovarian tissue vs ovarian carcinomas, bnormal ovarian tissue vs ovarian tissue carrying BRCA heterozygous mutations or prophylactic oophorectomy ovaries, and covarian tissue carrying BRCA heterozygous mutations or prophylactic oophorectomy ovaries vs ovarian carcinomas. Percentages represents positive or negative case number ratio.
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