Table 1 Distribution of EGFR copy number for each nonsmall cell lung carcinoma subtype by FISHa

From: Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma

Tumor subtype

Number of cases

 

Total

Nonamplified

Low polysomy

High polysomy

Gene amplified

Adenocarcinoma

28

5

4

16

2

Adenocarcinoma with bronchioloalveolar features

25

7

7

9

3

Bronchioloalveolar carcinoma

2

2

—

—

—

Squamous cell carcinoma

15

7

2

1

2

Adenosquamous carcinoma

7

1

1

2

2

Total

77

22

14

27

9

  1. aCISH and/or FISH assays failed in five cases (one adenocarcinoma, one adenocarcinoma with bronchioloalveolar features, two squamous cell carcinomas and one adenosquamous carcinoma).
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