Table 2 H-Ras mutations, the amino-acid change, cyclin D1 expression and survival status of the patients are shown
Sample no. | Site of tumour | Wild type | Mutation | Amino-acid change | Cyclin D1 expression | Recurrence |
|---|---|---|---|---|---|---|
Codon 12 | ||||||
60 | OS | GGC | AGC | Gly>Ser | Low | No |
65 | OS | GGC | AGC | Gly>Ser | Low | No |
99 | OS | GGC | AGC | Gly>Ser | High | Yes |
156 | OS | GGC | GAC | Gly>Asp | Low | No |
248 | OS | GGC | AGC | Gly>Ser | Low | No |
255 | OS | GGC | AGC | Gly>Ser | Low | No |
203 | T | GGC | AGC | Gly>Ser | High | No |
494 | OS | GGC | AGC | Gly>Ser | Low | No |
398 | OS | GGC | AGC | Gly>Ser | Low | No |
242 | OS | GGC | AGC | Gly>Ser | High | No |
178 | OS | GGC | AGC | Gly>Ser | Low | No |
90 | OS | GGC | AGC | Gly>Ser | Low | No |
Codon 13 | ||||||
152 | OS | GGT | TGT | Gly>Cys | Low | No |
154 | OS | GGT | GTT | Gly>Val | Low | No |
202 | OS | GGT | GTT | Gly>Val | Low | No |
237 | OS | GGT | CGT | Gly>Arg | High | No |
260 | OS | GGT | CGT | — | High | No |
GAT | — | |||||
153 | OS | GGT | GTT | Gly>Val | Low | No |
Codon 61 | ||||||
140 | OS | CAG | CTG | Gly>Leu | Low | No |
