Table 3 Variables showed significant association with H-Ras mutation
Variables | H-Ras mutation | χ2 P-value | Relative risk and 95% confidence interval | |
|---|---|---|---|---|
No mutation | Mutation | |||
Gender | ||||
Male | 93 (92.1) | 8 (7.9) | ||
Female | 40 (78.6) | 11 (21.6) | 0.016 | 3.2 (1.196–8.546) |
Oral sites | ||||
Other oral sites | 100 (84.7) | 18 (15.3) | ||
Tongue | 33 (97.1) | 1 (2.9) | 0.056 | 0.168 (0.022–1.310) |
Cyclin D1 | ||||
Low expression | 61 (81.3) | 14 (18.7) | ||
High expression | 70 (93.3) | 5 (6.7) | 0.027 | 0.311 (0.106–0.914) |
CDK4 | ||||
Low expression | 65 (82.3) | 14 (17.7) | ||
High expression | 67 (93.1) | 5 (6.9) | 0.046 | 0.346 (0.118–1.017) |
p16 | ||||
Low expression | 90 (91.8) | 8 (8.2) | ||
High expression | 42 (79.2) | 11 (20.8) | 0.026 | 2.9 (1.104–7.863) |
Rb | ||||
Low expression | 76 (93.8) | 5 (6.2) | ||
High expression | 56 (80.0) | 14 (20.0) | 0.011 | 3.8 (1.293–11.166) |
