Table 1 Summary of LOH loci tested

From: Loss of heterozygosity identifies genetic changes in chronic myeloid disorders, including myeloproliferative disorders, myelodysplastic syndromes and chronic myelomonocytic leukemia

Chromosome

Locus

Gene

7q31.1

D7S2554

Putative TSG

8q24

D8S263

Telomeric to MYC

9p21

D9S157

Telomeric to p16

9p21

D9S161

Centromeric to p16

13q14

D13S319

Telomeric to RB

17p13.1

p53

TP53

20q12

D20S108

Telomeric to C-SRC

  1. TSG, tumor suppressor gene.
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