Figure 2
From: Gain of chromosome 8q is a frequent finding in pleuropulmonary blastoma
Representative comparative genomic hybridization (CGH) picture with corresponding confirmatory fluorescence in situ hybridization (FISH) analysis of chromosome 8q gain, showing the CGH result in the right upper panel (a), and the result of the FISH analysis, with a probe for the centromere of chromosome 8, in the right lower panel (b). There is a clear increase in the number of FISH spots, resulting in up to five copies per nucleus. For comparison, the CGH result of chromosome 1 and the corresponding FISH experiment with a probe to the centromere of chromosome 1 are shown in the left upper and lower panel, respectively. In the FISH experiment, only two copies of chromosome 1 are present.
