Table 1 Clinicopathologic features of colorectal cancer patients and L1 expression in this study
From: L1 is associated with micrometastatic spread and poor outcome in colorectal cancer
Variable | Total | L1 negative | L1 positive |
---|---|---|---|
Total | 375 | 327 (87%) | 48 (13%) |
Age (years) | |||
 <60 | 122 (33%) | 102 (27%) | 20 (5%) |
 >60 | 253 (67%) | 225 (60%) | 28 (8%) |
Sex | |||
 Male | 224 (60%) | 191 (51%) | 33 (9%) |
 Female | 151 (40%) | 136 (36%) | 15 (4%) |
Localization | |||
 Ascending colon | 72 (19%) | 63 (17%) | 9 (3%) |
 Transverse colon | 23 (6%) | 21 (6%) | 2 (1%) |
 Descending colon | 7 (2%) | 5 (1%) | 2 (1%) |
 Sigmoid colon | 85 (23%) | 73 (20%) | 12 (3%) |
 Rectum | 188 (50%) | 165 (44%) | 23 (6%) |
Histological grading | |||
 G1 | 4 (1%) | 4 (1%) | 0 |
 G2 | 307 (82%) | 266 (71%) | 41 (11%) |
 G3 | 64 (17%) | 57 (15%) | 7 (2%) |
Tumor depth | |||
 pT1 | 18 (5%) | 16 (4%) | 2 (1%) |
 pT2 | 79 (21%) | 71 (19%) | 8 (2%) |
 pT3 | 235 (63%) | 201 (54%) | 34 (9%) |
 pT4 | 43 (12%) | 39 (10%) | 4 (1%) |
Lymph nodes | |||
 pN0 | 187 (50%) | 168 (45%) | 19 (5%) |
 pN1 | 89 (24%) | 74 (20%) | 15 (4%) |
 pN2 | 99 (26%) | 85 (23%) | 14 (4%) |
Metastasis | |||
 M0 | 289 (77%) | 241 (64%) | 48 (13%) |
 M1 | 86 (23%) | 86 (23%) | 0 |