Figure 4 | Modern Pathology

Figure 4

From: Gene expression and clonality analysis of the androgen receptor and phosphoglycerate kinase genes in polygonal cells and cuboidal cells in so-called pulmonary sclerosing hemangioma

Figure 4

The androgen receptor locus in pulmonary sclerosing hemangioma polygonal and surface cuboidal cells. In six cases, digestion of the adjacent tumor with HhaI produced two bands, indicating androgen receptor gene polymorphism and polyclonality. In cases 4 and 5, polygonal (P) and surface cuboidal cells (C) lost the long allele band; cases 9, 11, and 15 lost the short allele band; and the long allele band was significantly weaker in case 6 (due to unbalanced methylation, clonality ratio=0.19), indicating that P and C cells result from monoclonal proliferation. −, without HhaI digestion; +, with HhaI digestion; normal tissues (NT).

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