Figure 1 | Modern Pathology

Figure 1

From: CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer

Figure 1

Immunohistochemistry staining of MUC2 (a), MUC5AC (b), MUC6 (c), CDX2 (d) and Ki67 (f) and ABPAS staining (e) in a focus of complete IM (left part) and an adjacent focus of incomplete IM (right part). Besides the presence of MUC2-positive goblet cells, incomplete IM expressed gastric mucins (MUC5AC in almost all glands and Muc6 in several deeper glands) in goblet cells and columnar cells, while complete IM only expressed MUC5AC in few goblet cells but not in the absorptive cells. The CDX2 expression was significantly decreased in the incomplete IM than that in complete IM.

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