Figure 5 | Modern Pathology

Figure 5

From: Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas

Figure 5

E-cadherin nuclear translocation was also found in primary colorectal cancer and metastasis. E-cadherin nuclear translocation was detected in primary colorectal cancers and in some areas of the corresponding liver metastasis of a colorectal tumor with nuclear E-cadherin (a). Cytoplasmic and nuclear fractionation of tissue extracts verified nuclear translocation of E-cadherin as initially detected by immunohistochemical analysis (b). Histone H3 and GAPDH were used as nuclear and cytoplasmic markers, respectively.

Back to article page