Table 2 Abnormalities detected in esophagus tumors in the key components of the Wnt signaling pathway
Abnormal nuclear localization and expression | |
β-catenin | 13% (4/30) |
α-catenin | 17% (5/29) |
E-cadherin | 60% (18/30) |
Cyclin D1 | 46% (14/30) |
MYC | 73% (21/30) |
Increased cytoplasmic level | |
Axin2 | 48% (14/29) |
β-catenin | 50% (14/30) |
E-cadherin | 33% (10/30) |
α-catenin | 31% (9/29) |
GSK3α/β | 34% (10/29) |
