Figure 1 | Modern Pathology

Figure 1

From: WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer

Figure 1

Frequencies of mucinous tumors in WRN-methylated and WRN-unmethylated colorectal cancers within each of the 9 MSI/CIMP subtypes. Note that WRN-methylated tumors show consistently higher frequencies of mucinous differentiation (both ≥50% mucinous tumors and any mucinous tumors) than WRN-unmethylated tumors (P=0.004). Abbreviations: CIMP, CpG island methylator phenotype; M, methylated; MSI, microsatellite instability; MSS, microsatellite stable; UM, unmethylated.

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