Table 2b Immunohistochemistry study results for anaplastic carcinomas

From: Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms

 

Pax8

TTF-1

TTF-2

 

0

1+

2+

3+

4+

 

0

1+

2+

3+

4+

 

0

1+

2+

3+

4+

 

Squamoid

1

1

1

1

1

4/5 (80%)

4

1

0

0

0

1/5 (20%)

0

0

0

0

0

0/5 (0%)

Squamous cell

0

1

2

2

3

8/8 (100%)

8

0

0

0

0

0/8 (0%)

8

0

0

0

0

0/8 (0%)

Spindle

3

0

1

2

0

3/6 (50%)

5

1

0

0

0

1/6 (17%)

5

1

0

0

0

1/6 (17%)

Giant cell

0

0

0

0

2

2/2 (100%)

1

1

0

0

0

1/2 (50%)

1

1

0

0

0

1/2 (50%)

Epithelioid

2

2

1

0

0

3/5 (60%)

3

1

1

0

0

2/5 (40%)

5

0

0

0

0

0/5 (0%)

Rhabdoid

0

0

0

0

2

2/2 (100%)

2

0

0

0

0

0/2 (0%)

2

0

0

0

0

0/2 (0%)

  1. 0 indicates no staining; 1+, 1–25% tumor cells reactive; 2+, 25–50% tumor cells reactive; 3+, 50–75% tumor cells reactive; 4+, ≥75% tumor cells reactive.