Table 1 Characteristics of the study group and morphological data of the specimens studied

From: Aberrant fibrillin-1 expression in early emphysematous human lung: a proposed predisposition for emphysema

 

Normal (n=12)

Moderate degree of microscopical emphysema (n=27)

High degree of microscopical emphysema (n=30)

Study group

 Age (year)

60±9

61±8

65±6

 Pack years

29±9

38±20

39±21

 FEV1 (% pred.)

74±15

82±19

77±17

 FEV1/VC (% pred.)

82±1

91±1

78±2

 Kco (% pred.)

81±26

82±22

75±19

 TLC (% pred.)

93±23

95±17

102±13

 RV/TLC (% pred.)

105±21

106±21

108±18

Morphological data specimens

 DI (%)

25±10

58±8

83±7

 MLI (μm)

290±41

319±43

394±55

 PG (%)

31±11

57±9

78±8

  1. DI, Destructive Index; MLI, Mean Linear Intercept; PG, Panel Grading; FEV1, forced expiratory volume in 1 s; % pred., percentage of predicted value; VC, vital capacity; Kco, diffusion capacity for CO; TLC, total lung capacity; RV, residual volume.
  2. All values are means±s.d.
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