Table 2 Expression of mRNA and proteins for MART-1 and TRP-2 in nevi, primary and metastatic melanomas and keratinocytic tumors
MART-1 | TRP-2 | |||
---|---|---|---|---|
RT in situ PCR | IHC | RT in situ PCR | IHC | |
Primary melanoma | 24/26 (92%) | 23/24 (96%) | 17/26 (65%) | 20/24 (83%) |
In situ | 6/6 (100%) | 6/6 (100%) | 4/6 (67%) | 5/6 (83%) |
Invasive | 18/20 (90%) | 17/18 (94%) | 13/20 (65%) | 15/18 (83%) |
Metastatic melanoma | 9/9 (100%) | 9/9 (100%) | 6/9 (67%) | 9/9 (100%) |
Melanocytic nevi | 5/6 (83%) | 5/6 (83%) | 4/6 (67%) | 4/6 (67%) |
Squamous cell carcinoma | 0/4 (0%) | 0/4 (0%) | 0/4 (0%) | 0/4 (0%) |
Basal cell carcinoma | 0/4 (0%) | 0/4 (0%) | 0/4 (0%) | 0/4 (0%) |