Figure 1

Representative results of chromosome 17 CGH analysis confirmed by FISH of the p53 locus in three cases of malignant PCC. (a) Malignant PCC (case 15), not showing loss or gain in CGH and FISH analysis. (b) Malignant PCC (case 8) with loss of 17p in the CGH analysis, including the p53 gene locus, also showing loss in FISH. (c) Malignant PCC (case 13) showing gain of chromosome 17 in the CGH analysis and multiple p53 gene loci by FISH.