Table 3 Results of CGH analysis, FISH, SSCP analysis, and immunohistochemistry in benign PCC

From: Frequent loss of 17p, but no p53 mutations or protein overexpression in benign and malignant pheochromocytomas

Samples

Patients

Characteristics

CGH 17p

FISH p53

SSCP

IH

 1

1

F/62 sp/adr/u

 2

2

M/30 sp/adr/u

 3

3

F/41 sp/adr/u

 4

4

F/24 n/adr/u

 5

5

M/66 sp/adr/u

 6

6

M/49 m/adr/bi

 7

7

M/42 sp/adr/u

 8

8

M/47 sp/ea/u

 9

9

F/69 sp/adr/u

10

10

F/37 sp/adr/u

11

11

M/41 sp/adr/u

12

12

F/30 sp/adr/u

13

13

F/56 sp/ea/u

14

14

M/41 sp/adr/u

15

15

F/33 sp/adr/u

16

16

M/72 m/adr/bi I

17

 

II

18

17

M/40 m/adr/u

19

18

M/53 m/adr/bi I

20

 

II

21

19

F/33 sp/adr/u

22

20

F/44 sp/adr/u

23

21

M/24 m/adr/u

24

22

M/58 sp/adr/u

25

23

F/53 n/adr/u

26

24

M/53 sp/adr/u

27

25

F/59 sp/adr/u

28

26

F/49 sp/adr/u

29

27

F/48 sp/adr/u

30

28

F/24 m/adr/bi I

31

 

/27 II

32

29

F/59 m/adr/bi

33

30

M/43 sp/adr/u

  1. In CGH analysis, represents ‘no gain or loss,’ • is ‘loss,’ and means ‘gain’ of chromosome 17. In FISH analysis, is ‘retention of heterozygosity,’ • means ‘loss of heterozygosity,’ and represents ‘gain’ of the p53 locus on chromosome 17. In SSCP, means no mutation. In immunohistochemistry, represents ‘no overexpression’ and • means p53 protein overexpression. In all four techniques, — means that these samples are not examined. M=male; F=female; sp=sporadic; m=men; n=neurofibromatosis; adr=adrenal; ea= extra-adrenal; u=unilateral; bi=bilateral; LN=lymph node.