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Endosome dynamics regulated by a Rho protein

Abstract

Vesicular transport is a dynamic process that requires coordinated interactions between membrane and cytoskeleton. The mechanisms and molecules integrating these interactions are unclear. A Rho protein, RhoD, might provide a molecular link between membrane traffic and the cytoskeleton. Activated RhoD causes rearrangements of the actin cytoskeleton and cell surface, and governs early endosome motility and distribution.

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Murphy, C., Saffrich, R., Grummt, M. et al. Endosome dynamics regulated by a Rho protein. Nature 384, 427–432 (1996). https://doi.org/10.1038/384427a0

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