TABLE 4 Selected Summary of Uterine Non-Hodgkin's Lymphoma Reported in the Literature*

From: Non-Hodgkin's Lymphomas Involving the Uterus: A Clinicopathologic Analysis of 26 Cases

Study

Age (yr)

Sites (no.)

Presentation

Stages (no.)

Histologic type (no.)

Immunophenotype (no.)

Treatment (no.)

5-yr survival rate (%)

Harris and Scully (4) (n = 21)

20–80

Cervix (19), corpus (2)

AUB

IE (16) IIE (3) IV (2)

DLCL (12), FMCL (3), FLCL (3), FSCCL (1), Burkitt's (1), U (1)

B-cell (2)

Surgery (17), RT (12), CT (4)

57

Stroh et al. (15) (n = 13)

22–73

Cervix (7), corpus (4), unknown (2)

AUB

IE (5) IIE (4) IIIE (1) IV (3)

DLCL (11), SLL (1), FSCCL (1)

ND (13)

CT (13), RT (9)

70

Chorlton et al. (2) (n = 8)

34–51

Cervix (5), corpus (3)

Abdominal and pelvic mass

N/A

DLCL (3), U (3), SLL (1), DSCCL (1)

ND (8)

Surgery (5), RT (4), CT (3)

33

Aosaza et al. (1) (n = 7)

30–71

Cervix (4), corpus (3)

AUB

IE (2) IIE (3) IIIE (1) N/A (1)

DLCL (5), DM (1), U (1)

B-cell (7)

RT (4), surgery (4), CT (3)

0

Liang et al. (9) (n = 6)

25–78

Corpus + cervix (3), corpus (2), cervix (1)

N/A

IE (1) IV (5)

DLCL (4), LBL (1), DSNC (1)

B-cell (3), ND (3)

CT (6), RT (4)

0

Muntz et al. (13) (n = 5)

23–73

Cervix (5)

AUB

IE (5)

DLCL (3), DSCCL (1), FSCCL (1)

B-cell (3)

RT (5), surgery (3)

100

Monterroso et al. (12) (n = 5)

22–77

“Uterus” or corpus + cervix (3), corpus (2)

Abdominal and pelvic mass with ovarian NHL

IV (5)

DLCL (2), SNCB (2), follicular + diffuse LCL (1)

B-cell (5)

Surgery (5), CT (4)

N/A

Delgado et al. (3) (n = 4)

37–70

Cervix (4)

AUB

N/A

DLCL (4)

ND (4)

RT (3), surgery (1)

N/A

Iliya et al. (5) (n = 4)

44–70

Cervix (3), “uterus” (1)

AUB

IV (4)

DLCL (4)

ND (4)

RT (4), CT (3), surgery (1)

0

Johnson et al. (6) (n = 4)

40–67

Corpus (2), corpus + cervix (1), cervix (1)

AUB

IV (4)

LBL (2), DLCL (1), SLL (1)

ND (4)

RT (4)

N/A

Komaki et al. (7) (n = 3)

38–43

Cervix (3)

AUB

IIE (3)

DLCL (2), DM (1)

ND (3)

RT (3), CT (1)

100

Lathrop (8) (n = 3)

27–62

Cervix (1), “uterus” (1), corpus + cervix (1)

AUB

IV (3)

DLCL (2), small cleaved (1)

ND (3)

RT (3), CT (1), surgery (1)

0

Makarewicz and Kuzminska (10) (n = 3)

33–65

Cervix (3)

AUB

IE (2) N/A (1)

DLCL (1), FCL-D (1), LBL (1)

B-cell (3)

CT (3), RT (2), surgery (1)

N/A

Maryniak and Nasierowska-Guttmejer (11) (n = 3)

24–72

Cervix (3)

AUB

IE (1) IIE (2)

DLCL (2), DSCCL (1)

B-cell (3)

RT (3), surgery (2), CT (1)

0

van de Rijn et al. (16) (n = 3)

64–68

Corpus (3)

Variable

“Low stage” (3)

“low-grade” (3)

B-cell (3)

Surgery (3)

N/A

Osborne et al. (14) (n = 3)

11–70

“Uterus” (3)

All patients had ovarian lymphoma

IV (3)

DLCL (2), DSNC (1)

ND

Surgery (3), CT (1)

33

  1. AUB, abnormal uterine bleeding; NHL, non-Hodgkin's lymphoma; N/A, not available; DLCL, diffuse large cell lymphoma; FMCL, follicular mixed cell lymphoma; FLCL, follicular large cell lymphoma; FSCCL, follicular small cleaved cell lymphoma; U, unclassified; SLL, small lymphocytic lymphoma; DSCCL, diffuse small cleaved cell lymphoma; DM, diffuse mixed; LBL, lymphoblastic lymphoma; DSNC, diffuse small noncleaved cell lymphoma; SNCB, small noncleaved, Burkitt's type lymphoma; LCL, large cell lymphoma; FCL-D, follicle center lymphoma-diffuse, small cell; ND, not done; RT, radiation therapy; CT, chemotherapy.
  2. *Most of the listed diagnoses have been translated into the Working Formulation (when possible) because the cited studies originally used histologic diagnoses from many different classification systems; only Ann Arbor staging is reviewed.