TABLE 4 Relationship among P53 Expression, P53 Mutations, and Pathologic Characteristics

From: Discordance of P53 Mutations of Synchronous Colorectal Carcinomas

 

No. of Cases

Frequency of Cases (%)

  

P53 Expression

P53 Mutation

Tumor site

   

 Right side

7

1 (14%)b

3 (43)c

 Left side

14

12 (86)

10 (71)

 Rectum

11

10 (91)

10 (91)

Histologic differentiation

   

 Low grade

28a

19 (68)

24 (86)d

 High grade

4

2 (50)

1 (25)

  1. aa Including one mucinous carcinoma.
  2. bb Significant difference between right-sided tumors and left-sided tumors, including rectal tumors (p <.05, by Fisher's exact test).
  3. cc Significant difference between right-sided tumors and rectal tumors (p =.04, by Fisher's exact test).
  4. dd Significant difference between high-grade tumors and low-grade tumors (p <.05, by Fisher's exact test).
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