TABLE 2 Summary of Collagenous Gastritis Case Reports
From: Collagenous Gastritis: A Case Report, Morphologic Evaluation, and Review
Case Report | Current Report | Grossman 1996 (15) | Stolte 1990 (16) | Colletti 1989 (14) | Borchard 1989 (13) |
|---|---|---|---|---|---|
Age | 57 | 35 | 75 | 15 | 67 |
Sex | Male | Female | Female | Female | Female |
Clinical presentation | Diarrhea, rectal bleeding, malabsorption | Abdominal distension, watery diarrhea | Watery diarrhea for 6 mo | Intermittent gastric pain for 1 y | Watery diarrhea for 2 y |
Endoscopy | Gastric erythema, duodenal atrophy, rectosigmoid erythema and exudate | Diffuse gastric edema, nodularity | Not reported | Erythema, nodularity, hemorrhagic mucosa | Normal endoscopy |
Histology | Diffuse chronic gastritis | Patchy surface damage, nonspecific gastritis | Active chronic gastritis | Patchy, superficial active chronic gastritis | Active chronic gastritis |
Collagen | Antrum surface epithelium, mean 27 μ | Surface epithelium avg. 20–30 μ | Antrum, body surface epithelium 30–60 μ | Antrum surface epithelium avg. 25–30 μ | Location not specified 60 μ |
Lymphocytic gastritis | Yes | Not reported | Not reported | Not reported | Not reported |
Significant labs | IgA, gliadin, endomysial titers elevated, pANCA | Antigliadin G,A negative | Not reported | IgG,A,M,E, ANA, parietal cell and IF negative | No serum autoantibodies |
Associated diseases | Celiac sprue, mucosal ulcerative colitis | Lymphocytic colitis | Collagenous colitis, sprue | Normal esophageal, duodenal, colon biopsies | Collagenous sprue, collagenous colitis |
Treatment | Asacol, gluten restriction | Sucralfate, famotene, sulfasalazine | Not given | Ranitidine, sucralfate, furazolidane | Loperamide |
Course | Resolution of diarrhea and gastrointestinal bleeding | Resolution of diarrhea only | Not given | No clinical/ pathologic resolution | Residual gastric collagen at rebiopsy |
