FIGURE 1 | Modern Pathology

FIGURE 1

From: Trichoblastic Carcinoma (“Malignant Trichoblastoma”) with Lymphatic and Hematogenous Metastases

FIGURE 1

A, scanning view of the deep dermal cutaneous neoplasm, consisting of a solid tumor with focal cystic degeneration (×1.25). B, residual lobules of trichoblastoma consisting of basaloid cells and calcifications adjacent to the malignant proliferation (×20). C, follicular germinative cells with peripheral nuclear palisading. D, infundibulocystic structures with pale cells, matrical material, and dystrophic melanin- containing hair shafts (×128). E, foreign body giant cells, bone formation adjacent to malignant proliferation (×128). F, solid malignant proliferation around preexisting infundibulocystic structure (×50). G, spindle cells in fascicular arrangement (×200). H, tightly packed nests reminiscent of embryonic follicular germ cells (×128).

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