FIGURE 1

Patient 1. A, Posteroanterior chest radiograph demonstrating diffuse bilateral interstitial opacities. There is evidence of prior sternotomy and pleural thickening and/or fluid of unknown chronicity. B, C, high-resolution CT scan of the lung demonstrating diffuse bilateral smooth thickening of the interlobular septa throughout the lung. Foci of cystic lung disease are present in the mid-right lung. There is also thickening of the fissures. Note the osseous sclerosis of the vertebral body in B. D, Posteroanterior chest radiograph obtained 5 years after the image in A demonstrating marked progression of interstitial lung disease and increased pleural thickening.